Czech Republic (the)
Faculty of Science, Charles University| The award | How you will study | Study duration | Course start | Domestic course fees | International course fees |
|---|---|---|---|---|---|
| PhD | Full-time | - | - | - | - |
Peroxisomes are spherical organelles of 0.2-1.5 ?m diameter surrounded by a single membrane that are found in all eukaryotic cells and are essential for various metabolic pathways. These organelles are a metabolic hub as they host numerous metabolic pathways such as ?-oxidation of fatty acids and metabolism of reactive oxygen and nitrogen species, the latter playing an important role, e.g., in the function of the male gametophyte. Plant peroxisomes function cooperatively with other organelles such as mitochondria, chloroplasts and oil bodies through contacts sites that enable exchange of metabolic products between these organelles. Peroxisomes are highly plastic and motile and move rapidly on the actin cytoskeleton. We suggested that the cytoskeleton is involved in peroxisomal membrane remodelling, because we found out that peroxisomes are associated with cytoskeleton-nucleating factors. The goal is to uncover the mechanism of peroxisome-cytoskeleton interaction by means of methods of co-immunoprecipitation/protein mass spectrometry analysis, superresolution microscopy and correlative light electron microscopy methods (CLEM). Identification of protein interactors and their localization co-by CLEM will allow to determine the function of the cytoskeleton in peroxisome membrane remodeling. Applicants should have the experience in fluorescence and/or confocal microscopic analysis of living cells.
Five relevant publications of the research group:
Martinek, J., Cifrov
Contact Faculty of Science, Charles University to find course entry requirements.
Below are some suggested courses at other providers that you may also be interested in:
MSc International Business 4.0 - Luxury Marketing & Fashion Management MSc
ESSCA School of Management – Online Programs
Find out more
If you do not meet the entry requirements for this course then consider one of these postgraduate preparation courses from another institution:
Graduate Diploma of Engineering (Electrical Systems)
Engineering Institute of Technology
Find out more
Graduate Diploma in Law/Common Professional Examination GDL/CPE
Northumbria University Newcastle
Find out more
There are 136 other courses listed from Faculty of Science, Charles University. A selection of these are displayed below:
A postdoctoral position to study thermal effects in landslides Postdoc
Faculty of Science, Charles University
Find out more Activation of STING signaling in tumors associated with human papillomaviruses PhD
Faculty of Science, Charles University
Find out more Advanced Electron Microscopy Techniques for the Characterization of Tunable Zeolitic Architectures PhD
Faculty of Science, Charles University
Find out more Amphiphilic Peptidomimetics Containing Metallacarboranes as a Design Strategy for Future Antibiotics PhD
Faculty of Science, Charles University
Find out more Join the StudyLink email list and never miss a chance to turn your study abroad dreams into reality!
See other universities in Prague
Find out more about studying in Czech Republic (the)
