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Pharmacy, MPhil, PhD, MD, Newcastle University

the United Kingdom

Newcastle University

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The award How you will study Study duration Course start Domestic course fees International course fees
MPhil, PhD, MDFull-time, Part-time12 - 24 monthsfind outfind outfind out

About Pharmacy, MPhil, PhD, MD - at Newcastle University

We have scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy. This spans the fundamental understanding and concepts of drug action, the discovery of new drugs and development of medicines, the clinical management and rationale use of medicines, through to the professional role of the pharmacist in improving public health.

As a postgraduate research student studying for an MPhil or PhD, you will be based within the School of Pharmacy and a research institute in the Faculty of Medical Sciences relevant to your proposed research. Our research institutes are as follows:

  • Ageing
  • Cell and Molecular Biosciences 
  • Cellular Medicine
  • Health and Society
  • Genetic Medicine
  • Neuroscience
  • Cancer Research

If your research involves clinical components there may be a partnership with the NHS.

The School of Pharmacy's focus is on multidisciplinary translational research, work that is relevant to real life. We combine world-class laboratory and clinical research facilities with an open environment where scholars, clinicians and researchers benefit from working side-by-side. You will spend your time within research teams led by experts in their field, in a friendly and supportive atmosphere.

We offer MPhil and PhD supervision in the following research areas:

Disease-Selective Medicines

The discovery and development of new small molecule therapeutics with improved disease selectivity and reduced systemic toxicities, through the use of rational drug design and synthesis, lead optimisation, and preclinical evaluation in cellular disease model systems. We are particularly interested in the development of cancer prodrugs with tumour specific activation and reduced systemic toxicity, and novel therapies for improved treatment of infective diseases including Dengue and other haemorrhagic fever viruses and Tuberculosis, amongst others.

Improved Strategies for the Treatment of Chronic Pain

Understanding the molecular mechanisms that generate and maintain the symptoms and processes of chronic pain, and its translation to effective strategies for pain control, including opioid treatment.

Cellular Physiology

Understanding the pathways that allow hormones to control epithelial ion channel activity and physiological action, particularly the control of sodium channel activity in the distal nephron and consequent hypo/hyper-tension.

Safety Pharmacology and Discovery Toxicology

Development and utilisation of new preclinical tools for identification of therapeutics with potential safety liabilities, particularly novel clinically relevant cell models and systems for detection of effects upon the heart.

Pharmaceutics and Chemical Principles of Dosage Form Design

Pharmaceutical formulations to deliver active molecules to treat disease. We have active research on intermolecular interactions, nanoscale pharmaceutics and nanotherapeutics, including dosage form design from intermolecular interactions, and delivery of biopharmaceuticals. In particular research is focused on:

  • determining strategies for improving drug solubility and altering materials properties to enable effective drug delivery and the production of enhanced medicines.
  • supramolecular Pharmaceutics, particularly inter/intramolecular interactions and kinetics leading to, during and after self-assembly of small organic molecules.
  • fundamental and translational nanomedicines
  • understanding and improving drug delivery via the subcutaneous, inhaled and intravitreal routes of delivery

Pharmaceutical Public Health

The role of community pharmacy as a central fulcrum to address health inequalities and behaviour change in relation to smoking, alcohol and substance misuse, sexual health and obesogenic behaviours, amongst others. As the community pharmacy is the most frequent point of contact for patients and public within the wider primary healthcare team, we evaluate the dynamics and interactions of this relationship and the potential role for pharmacy within the early diagnosis of disease and improvements in public health.

Rational Medicines Use

The safe and efficient use of medicines in primary and secondary care is central to the role of every pharmacist. However, medicines are becoming increasingly complex and patients are being given more preventative medicine focused at improving their health, which poses clear risks and significant potential for complications. Rationalisation of medicine usage crosses care boundaries, applies both within primary and secondary care, and furthermore at the care interface. We investigate prescribing habits and the mechanisms to support patients who may take complex medicines for a significant portion of their life

Patient Safety and Health Information Technology

Medication errors can result in patient injury or death, and are preventable. These errors can occur at the stages of ordering, transcription, dispensing and administration. We conduct studies around key technological advances targeted towards intercepting these errors and improving patient safety. Our research focuses on evaluation of specific health information technology prevention strategies throughout the medication use process, with a particular emphasis on health information technology, including its broader implications for medical care and policy. We also explore the different types and causes of errors that occur during the prescribing process when using electronic systems, providing national and international recommendations for their improvement.

Entry requirements

MPhil:

2:1 honours degree, or international equivalent, in a science or medicine related subject.

PhD:

2:1 honours degree, or international equivalent. Further research experience or a master’s degree would be advantageous.

MD:

MBBS, or an equivalent medical degree.

English Language Requirements

To study this course you need to meet the following English Language requirements:

IELTS 6.5 overall (with a minimum of 5.5 in all other sub-skills).

Our typical English Language requirements are listed as IELTS scores but we also accept a wide range of English Language tests.

You may need an ATAS (Academic Technology Approval Scheme) clearance certificate. You'll need to get this before you can get your visa or study on this programme. We'll let you know about the ATAS requirement in your offer letter.

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