Molecular Medicine, University of Sheffield

University of Sheffield the United Kingdom

For more information about Molecular Medicine at University of Sheffield, please visit the webpage using the button above.

The award

How long you will study
1 Years

Domestic course fees
GBP 10800 per year

How you will study

Course starts

International course fees
GBP 26200 per year

All study options

About Molecular Medicine at University of Sheffield

Lead academic: Dr Martin Nicklin

Designed for both animal/human biology and clinical graduates, this flexible course focuses on the molecular and genetic factors of human diseases. Understanding these factors is crucial to the development of therapies.

The course will

  • provide you with an understanding of both the background and the current technical and scientific advances in biomedical science and therapeutic design.
  • teach you how to use the latest technology to answer research questions
  • emphasise how experiments and experimental programmes are designed and interpreted.
  • provide you with an experience of a hypothesis-driven laboratory research project alongside experts in the field

All the above will increase your employability in both industry and academia, as well as being an excellent route to a PhD. It will also provide valuable transferable skills that you can use in whatever career path you choose.

Two-year post-study work visa

The UK government has announced a two-year post-study work visa for international students.

Your research project

We also give you practical lab training to prepare you for your research project. The project is five months of invaluable laboratory experience: planning, carrying out, recording and reporting your own research.

Examples of research projects

This list shows projects that students chose in 2017-2018. To protect intellectual property we haven't displayed the most recent projects as they are likely to relate to current research in the investigator's group. We usually generate a surplus of at least 30 per cent of projects. Students are guaranteed one of their top five choices and usually get their first or second choices. These projects are grouped by pathway title but almost all projects were available across more than one pathway.


  • Inducing breast cancer immunogenic cell death with Cancer Killing Viruses
  • The role of voltage gated sodium channels in the invasiveness and metastatic potential of cancer cells
  • Understanding the role of microtubule dynamics in the homeostasis of axonal transport and chemotherapy induced peripheral neuropathy
  • Transcriptomic and cell cycle analysis of THAP8-deficient cells
  • Targeting the endogenous cannabinoid system as alternative to medicinal marijuana for the treatment of prostate cancer
  • Elucidating the cellular pathways and machinery involved in epithelial polarisation and cancer using advanced imaging techniques
  • DNA replication complexes of the 'high cancer risk' human papillomaviruses (HPV) as targets for anti-viral/anti-cancer therapies
  • The small heat shock protein [alpha]B-crystallin (HSPB5) as a regulator of fibrosarcoma response to chemotherapy and radiotherapy

Experimental medicine

  • Investigating the effect of inflammation on veratridine response-profiles in primary sensory neurons
  • Developing a bi-functional non-antibiotic biodegradable wound dressing for treating chronic ulcers
  • Regulation of BPIFA2: an unexplored role in acute kidney disease
  • Development of microfabricated smart scaffolds for bone regeneration
  • Do neutrophil-derived microvesicles affect lung epithelial cell permeability?
  • Modulating cilia in the mucociliary airway epithelium
  • Chronic inflammatory disease in obesity: is leptin driven adipocyte-macrophage inflammatory signalling dependent on TRIB3?
  • Therapeutic potential of GSK3[beta] inhibition for anxiety and depression
  • Investigation of the generation of force by fibroblasts under the influence of therapeutic ultrasound
  • Novel strategy for intraneuronal delivery of proteins for treatment of neurological diseases
  • Is packaging of vault RNAs into extracellular vesicles dependent on major vault protein?

Microbes and infection

  • The potential of anti-adhesion therapy in a biofilm infection model
  • Role of FlrB in the regulation of bacterial motility and colonisation
  • Treating Respiratory Syncytial Viral Infection by Targeting Membrane Microdomains
  • The regulation of rhinoviral infection of the human airway by APPL1 and APPL2
  • Colicin M derivatives as novel antimicrobials against antibiotic resistant Gram-negative bacteria

Genetic mechanisms

  • Identification of neuronal kill factors secreted by stem cell-derived astrocytes from amyotrophic lateral sclerosis (ALS) patients
  • DNA damage and repair mechanisms in cellular models of TDP-43 mediated neurodegeneration
  • Is SENP1-mediated deSUMOylation of XBP1 Required for Autophagy Induction by ER stress for Cell Survival?
  • Characterization of miRNAs targeting TRIB1 and their impact on macrophage function, polarization and lipid metabolism
  • In silico functional analysis of inherited cancer susceptibility variants on chromosome 2


We accept medical students who wish to intercalate their studies. Find out more on the Medical School's website.

Study options for this course

  • The award How you will study How long you will study Course starts Domestic course fees International course fees
  • The awardMScHow you will studyFull-timeHow long you will study1 year
    Course startsSeptemberDomestic course feesGBP 10800 per yearInternational course feesGBP 26200 per year

Notes about fees for this course

For the Clinical pathway use our course fee lookup tool.

Entry requirements

You'll need at least a 2:1 undergraduate honours degree including a substantial element of human or animal biology.

We also accept medical students who wish to intercalate their studies.

We also consider a wide range of international qualifications:

Entry requirements for international students

Overall IELTS score of 7.0 with a minimum of 6.5 in each component, or equivalent.

Overall IELTS score of 6.5 with a minimum of 6.0 in each component, or equivalent.

Related Information

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