Genomic Approaches to Drug Discovery, University of Sheffield

University of Sheffield the United Kingdom

For more information about Genomic Approaches to Drug Discovery at University of Sheffield, please visit the webpage using the button above.

The award
MSc

How long you will study
1 Years

Domestic course fees
GBP 13000 per year

How you will study
full-time

Course starts
September

International course fees
GBP 28500 per year

All study options

About Genomic Approaches to Drug Discovery at University of Sheffield

This unique research-led masters course is for students who are fascinated by genomic technologies. You'll be provided with practical laboratory training in drug screening and gene discovery, using the latest automated genomics techniques.

We're home to the internationally renowned Sheffield RNAi Screening Facility (SRSF), which is kitted out with the same pioneering equipment that's used by pharmaceutical companies around the world. During your studies, you'll have the opportunity to work within the purpose-built SRSF and train to use technologies for drug screening, laboratory automation, cellular assays, imaging and processing.

You'll learn how to use high-throughput machinery that you'll find in industrial research facilities and develop skills in techniques including genome editing, 3D cell culture, robotics, and functional genomic screening. You'll also discover how academic labs, as well as those in the biotechnology and pharmaceutical industries use these same cutting-edge techniques to identify candidates for potential therapies. We'll then show you how to program a Hamilton Star liquid handling robot, used in many automation laboratories, as well as how to use and write algorithms for High Content Microscopy.

Practical training will be supported by theoretical sessions, teaching you about the latest techniques including T-cell therapies, antibodies, gene therapy, cell therapy, CRISPR, RNAi and clinical trials, so that you develop an appreciation of every step that's involved in the academic and commercial drug discovery process.

The most substantial part of the course is the research project. You'll spend three months working within the SRSF, honing your professional skills in the use of pharmacogenomics. You'll choose your research area from a range of projects to match your future career aspirations. This could cover cancer drug screening, target identification, gene delivery or peptide therapy projects. You could even choose to do a project away from the SRSF in another lab within the School of Biosciences.

Example research projects include:

  • An in vivo chemical screen for antagonists of an adhesion
  • GPCR signalling pathway in zebrafish
  • New strategies for cancer drug development: protein-protein interaction inhibitors to inhibit the critical cancer target Fen1
  • Understanding hypothalamic development: a scRNA seq approach

This course will give you the practical experience you need for an exciting career in the field of drug discovery. Alongside your training, you'll also get direct exposure to industry leaders from a wide range of companies. You'll build your professional network and gain a deeper understanding of how pioneering techniques and equipment are used in practice.

Intercalation

We accept medical students who wish to intercalate their studies. Find out more on the Medical School website.

Study options for this course

  • The award How you will study How long you will study Course starts Domestic course fees International course fees
  • The awardMScHow you will studyFull-timeHow long you will study1 year
    Course startsSeptemberDomestic course feesGBP 13000 per yearInternational course feesGBP 28500 per year

Notes about fees for this course

Fees for 2023 entry are not yet available. Please use these 2022 fees as a guide

Entry requirements

Minimum 2:1 undergraduate honours degree in a biomedical-related subject.

We also accept medical students who wish to intercalate their studies.

We also consider a wide range of international qualifications:

Entry requirements for international students

Overall IELTS score of 6.5 with a minimum of 6.0 in each component, or equivalent.

If you're an international student who does not meet the entry requirements for this course, you have the opportunity to apply for a pre-masters programme in Science and Engineering at the University of Sheffield International College. This course is designed to develop your English language and academic skills. Upon successful completion, you can progress to degree level study at the University of Sheffield.

Related Information

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